Anapiro® Solution For Injection

Anapiro® is a specialized veterinary broad-spectrum antimicrobial and antiparasitic injectable combination formulated to treat mixed systemic infections, rickettsial diseases, and blood-borne protozoan parasites in cattle, horses, swine, sheep, and goats operating under professional veterinary supervision. Combining a potent broad-spectrum tetracycline antibiotic with an effective anti-protozoal agent within a sterile injectable vehicle, this professional-grade therapeutic preparation delivers targeted dual-action control against concurrent bacterial and hemoparasitic pathogens. Because of its complex pharmacological profile and systemic impact, the administration of Anapiro requires precise clinical diagnosis, individualized weight-based dosing, and strict adherence to professional veterinary guidelines.

What Is Anapiro®?

Anapiro is a specialized veterinary therapeutic compound formulated for parenteral administration under professional clinical supervision.

Active Ingredients and Formulation (Per mL)

• Oxytetracycline Hydrochloride (100 mg): A broad-spectrum bacteriostatic antibiotic that inhibits protein synthesis across a wide range of gram-positive and gram-negative bacteria, rickettsia, and anaplasma species.

• Diaceturate (Diampron / Diminazene Diaceturate) (50 mg): A potent anti-protozoal agent targeted against blood parasites such as Babesia and Trypanosoma species.

• Vehicle and Presentation: Formulated as a sterile aqueous or suspension injectable solution designed for controlled veterinary dispensing and deep intramuscular administration in large animals.

What Is Anapiro Used For?

Primary Veterinary Indications

• Hemoparasitic Infections: Routinely utilized by livestock producers and equine veterinarians to treat tick-borne blood parasites, including bovine anaplasmosis (Anaplasma marginale) and babesiosis (piroplasmosis).

• Mixed Bacterial and Systemic Pathogens: Formulated to control secondary bacterial complications, respiratory infections, and systemic rickettsial diseases responsive to oxytetracycline therapy.

• Convalescence and Herd Health Support: Assists in stabilizing livestock confronting acute multi-pathogen vectors common in endemic grazing regions.

Administration and Dosage Considerations

Route and Dosing

• Route of Administration: Administered via deep intramuscular (I.M.) injection utilizing rigorous aseptic techniques to prevent localized tissue irritation or microbial contamination. Do not administer intravenously.

• Standard Dosage Reference: Typically calculated based on body weight (e.g., standard baseline formulations often approximate 6.6 mg of oxytetracycline and 3.3 mg of diaceturate per kg of body weight, or corresponding volume metrics like 1 ml per 15 kg body weight).

• Veterinary Supervision: Exact dosage schedules, frequency of administration, and total treatment duration must be determined and monitored exclusively by a qualified veterinarian based on the individual animal’s body weight, species, and clinical diagnosis. Never guess or extrapolate dosages.

Important Safety Information

• Contraindications: Do not administer to animals with known hypersensitivity to oxytetracycline or diamidine compounds, or to patients with severe acute renal or hepatic impairment.

• Side Effects and Precautions: Can occasionally induce localized inflammatory reactions or pain at the injection site. High or repetitive dosing requires careful monitoring due to potential systemic toxicity associated with anti-protozoal constituents.

• Withdrawal Periods: Mandatory meat and milk withdrawal intervals established by local regulatory authorities must be strictly observed prior to marketing animal products for human consumption following treatment.

• Professional Guidance: Due to its potent antimicrobial and antiparasitic properties, use must be strictly supervised by a licensed animal health professional.

Storage and Handling

• Store at controlled room temperature between 15°C and 25°C (59°F to 77°F), protected from direct sunlight, excessive heat, and freezing temperatures.

• Maintain strict aseptic technique when puncturing multi-dose vials to prevent microbial contamination during repeated use.

• Keep securely out of reach of children, unauthorized individuals, feedstuffs, and animals at all times.

Species: 
Beef and dairy cattle, horses, swine, sheep, and goats.

Dosage:
Beef and dairy cattle, horses, swine, sheep, and goats: 1 ml/ 15 kg BW or 6.6 mg Oxytetracycline, 3.3 mg Diaceturate per kg BW Frequency: Every 24 h. Suggested duration: 3 days.

Differences:

• Anapiro 2 x 1 g (20 ml vial):
  Capacity: Recommended for a total treatable weight less than 300 kg BW.
  Use: Generally for young, small animals or for a smaller number of animals.
• Anapiro 3 x 1.5 g (30 ml vial):
  Capacity: Recommended for animals > 300 kg BW.
  Use:  Larger presentation, ideal for adult cattle or horses that require a higher dosing volume due to their weight.

Withdrawal Period:
30 days. Milk: 60 hrs.

Contraindications:
Do not administer to patients with known hypersensitivity to any of the components of the formula. Do not mix with other medications or products. Do not administer by any route other than IM.

Warnings:
Oxytetracycline has an affinity for chelating calcium ions, which leads to deposition in bone tissue and growing dentin. Oxytetracycline has a synergistic effect with Erythromycin and Neomycin but is antagonistic with Penicillin.

Frequently Asked Questions

What is Anapiro used for?

It is a professional veterinary combination injection utilized to treat tick-borne blood parasites (such as anaplasmosis and babesiosis) alongside concurrent bacterial infections in large animals.

What are the active ingredients in Anapiro?

It contains oxytetracycline hydrochloride for broad-spectrum bacterial coverage combined with diaceturate (diminazene) for targeted anti-protozoal activity.

How is Anapiro administered?

It is administered via deep intramuscular injection under the direct supervision of a qualified veterinarian based on precise body weight calculations.

Order Anapiro Online

Anapiro is available for order through our platform subject to full compliance with local regulatory requirements. For assistance regarding stock availability, secure ordering protocols, or delivery options, please contact our customer support team.