Naxcel (Ceftiofur Sodium) Sterile Powder for Injection, 1 g or 4 g Vial

Naxcel Sterile Powder is a high-potency veterinary broad-spectrum cephalosporin antibiotic formulated for intramuscular or subcutaneous administration in horses, cattle, swine, and other approved species to treat acute bacterial respiratory infections, foot rot, and soft tissue pathologies. Containing the active third-generation cephalosporin ceftiofur sodium, this professional-grade therapeutic preparation disrupts bacterial cell wall synthesis to eradicate susceptible Gram-positive and Gram-negative pathogens. Because of its broad antimicrobial spectrum and critical role in veterinary medicine, administration requires accurate diagnostic evaluation, precise weight-based reconstitution, and strict clinical oversight.

What Is Naxcel Sterile Powder?

Naxcel is a specialized veterinary broad-spectrum cephalosporin compound formulated for parenteral delivery under professional veterinary supervision.

Active Ingredients and Formulation

• Active Component: Ceftiofur sodium equivalent to 1 g or 4 g of ceftiofur per vial, which must be reconstituted with sterile water for injection prior to use. It acts as a bactericidal beta-lactam antibiotic that inhibits bacterial cell wall synthesis.

• Vehicle and Presentation: Supplied as a sterile, lyophilized white to off-white powder packaged in single-dose or multi-dose glass vials designed for aseptic reconstitution into a stable injectable suspension.

What Is It Used For?

Primary Veterinary Indications

• Equine Respiratory Infections: Routinely prescribed by equine veterinarians to treat lower respiratory tract infections caused by susceptible organisms such as Streptococcus equi subsp. zooepidemicus.

• Bovine Respiratory Disease (BRD): Utilized in cattle to control and treat shipping fever associated with Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni.

• Bovine Foot Rot and Acute Metritis: Indicated for the treatment of acute interdigital necrobacillosis (foot rot) and acute metritis in dairy cattle.

Administration and Dosage Considerations

Route and Dosing

• Route of Administration: Administered via intramuscular (I.M.) or subcutaneous (S.C.) injection after careful reconstitution with the appropriate volume of sterile water.

• Standard Equine Dosage Reference: Typically administered at 2.2 mg to 4.4 mg per kg (1.0 mg to 2.0 mg per lb) of body weight daily by intramuscular injection for 10 consecutive days.

• Standard Bovine Dosage Reference: Typically administered at 1.1 mg to 2.2 mg per kg (0.5 mg to 1.0 mg per lb) of body weight daily subcutaneously or intramuscularly for 3 to 5 days.

• Veterinary Supervision: Reconstitution ratios, dosage calculations, and treatment duration must be determined and managed exclusively by a licensed veterinarian.

Important Safety Information

• Contraindications: Do not administer to animals with known hypersensitivity or severe allergic reactions to ceftiofur or other beta-lactam antibiotics (penicillins and cephalosporins).

• Side Effects and Precautions: Generally well tolerated. Injection site discomfort or localized swelling may occasionally occur. As with all beta-lactams, allergic reactions ranging from mild skin rashes to acute anaphylaxis are possible in sensitive animals.

• Withdrawal Periods: Observe mandatory meat and milk withdrawal intervals established by regulatory authorities if treating food-producing livestock or equines intended for human consumption (typically 4 days for meat in cattle, with zero-hour milk discard depending on specific regional approvals).

• Professional Guidance: Due to its active systemic pharmacological profile and importance in antimicrobial stewardship, use must be managed under direct veterinary clinical oversight.

Storage and Handling

• Unreconstituted Powder: Store unopened vials at controlled room temperature between 15°C and 30°C (59°F to 86°F), protected from excessive heat and moisture.

• Reconstituted Solution: Once mixed with sterile water, store under refrigeration (2°C to 8°C / 36°F to 46°F) and use within the manufacturer’s specified timeframe (typically up to 7 days).

• Safety: Keep securely out of reach of children, unauthorized individuals, and animals at all times.

Frequently Asked Questions

What is Naxcel Sterile Powder used for?

It is a professional broad-spectrum cephalosporin antibiotic injection utilized to treat bacterial respiratory infections, foot rot, and systemic illnesses in horses, cattle, and swine.

What is the active ingredient?

It contains ceftiofur sodium (1 g or 4 g per vial), a bactericidal third-generation cephalosporin that disrupts bacterial cell wall formation.

How is Naxcel prepared and administered?

The lyophilized powder is reconstituted with sterile water for injection and administered daily via intramuscular or subcutaneous injection following precise weight-based guidelines under veterinary supervision.

Order Rx Naxcel Sterile Powder Online

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