Maropitant Citrate Tablets for Dogs

Maropitant Citrate Tablets are a specialized veterinary neurokinin-1 ($NK_1$) receptor antagonist formulated for oral administration in dogs and puppies to prevent and treat acute vomiting and prevent chemotherapy-induced nausea. Containing the active targeted antiemetic compound maropitant citrate, this professional-grade therapeutic preparation blocks the binding of substance P in the central nervous system to effectively halt the emetic reflex at its core. Because targeted antiemetic therapy requires accurate weight-based dosing and veterinary diagnostic evaluation of underlying conditions, administration must be guided by clinical supervision.

What Is Maropitant Citrate?

Maropitant citrate is a specialized veterinary neurokinin-1 receptor antagonist formulated for oral delivery under professional veterinary supervision.

Active Ingredients and Formulation

• Active Component: Maropitant citrate at specific milligram strengths per tablet (16 mg, 24 mg, 60 mg, or 160 mg). It acts as a selective $NK_1$ receptor antagonist, blocking substance P in the brainstem vomiting center to inhibit both central and peripheral emetic signals.

• Vehicle and Presentation: Supplied as scored oral tablets packaged in blister packs or bottles designed for precise, customizable dosing across canine patients 8 weeks of age and older.

What Is It Used For?

Primary Veterinary Indications

• Acute Vomiting Prevention and Treatment: Routinely prescribed by veterinarians to prevent and treat acute vomiting episodes resulting from various clinical etiologies.

• Chemotherapy-Induced Nausea Prevention: Indicated for the prevention of acute vomiting associated with cancer chemotherapy treatments.

• Motion Sickness Prevention: Utilized off-label or via specialized veterinary protocols to mitigate acute nausea and vomiting associated with vehicular travel.

Administration and Dosage Considerations

Route and Dosing

• Route of Administration: Administered orally, with a small amount of food to avoid digestive upset or given directly. Do not wrap tablets in heavy fatty foods if the dog is actively vomiting.

• Standard Canine Dosage Reference:

  • For Acute Vomiting: Administered at 1 mg/kg (0.45 mg/lb) of body weight once daily for up to 5 consecutive days.

  • For Prevention of Motion Sickness: Administered at 8 mg/kg (3.6 mg/lb) of body weight once daily for up to 2 consecutive days, given 2 hours prior to travel.

• Veterinary Supervision: Diagnosis of the underlying cause of vomiting must be confirmed by a licensed veterinarian before initiating ongoing antiemetic therapy.

Important Safety Information

• Contraindications: Do not administer to dogs with known hypersensitivity to maropitant. Do not use in puppies under 8 weeks of age. Use with caution in dogs with hepatic dysfunction or underlying cardiac disease.

• Side Effects and Precautions: Generally exceptionally well tolerated. Occasional side effects may include hypersalivation, decreased appetite, lethargy, or mild diarrhea. Pain or discomfort may occur if tablets are given without food or if scored tablets break down prematurely in the mouth.

• Professional Guidance: Long-term or continuous daily administration beyond recommended treatment windows should be managed exclusively under direct veterinary evaluation.

Storage and Handling

• Store at controlled room temperature between 15°C and 30°C (59°F to 86°F). Protect product from excessive moisture and light.

• Keep individual tablets in their protective packaging until ready for immediate administration.

• Keep securely out of reach of children, unauthorized individuals, and pets at all times.

Frequently Asked Questions

What is Maropitant Citrate used for?

It is a professional veterinary antiemetic tablet utilized to prevent and treat acute vomiting, manage chemotherapy-induced nausea, and prevent motion sickness in dogs.

What is the active ingredient?

Each tablet contains maropitant citrate, a targeted neurokinin-1 ($NK_1$) receptor antagonist that blocks substance P to shut down the vomiting reflex.

How is Maropitant Citrate administered?

It is administered orally once daily, with specific dosing regimens tailored depending on whether it is used for general acute vomiting or motion sickness prevention.

Order Maropitant Citrate Tablets Online

Rx Maropitant Citrate Tablets for Dogs are available for order through our platform subject to veterinary prescription verification and regulatory compliance. For assistance regarding prescription submission, stock availability, or secure shipping protocols, please contact our customer support team.