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Vetmedin (pimobendan) Chewable Tablets for Dogs

Vetmedin is for the treatment of congestive heart failure in dogs. As the first of a new class of heart treatments termed Inodilators, Vetmedin has been shown to significantly improve the clinical signs and extend the life expectancy in dogs with congestive heart failure. Vetmedin works through two complementary modes of action; it opens up the blood vessels taking blood to and away from the heart, thereby lowering the pressure on the heart and reducing the work the heart has to do to pump blood around the dog’s body. At the same time, Vetmedin has a direct effect on the heart muscle, helping it to beat stronger and pump blood more efficiently.

Vetmedin (pimobendan) is supplied as oblong half-scored chewable tablets containing 1.25 or 5 mg pimobendan per tablet. Pimobendan, a benzimidazole-pyridazinone derivative, is a non-sympathomimetic, non-glycoside inotropic drug with vasodilatative properties. Pimobendan exerts a stimulatory myocardial effect by a dual mechanism of action consisting of an increase in calcium sensitivity of cardiac myofilaments and inhibition of phosphodiesterase (Type III). Pimobendan exhibits vasodilating activity by inhibiting phosphodiesterase III activity.

Price range: $69.00 through $165.00

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Features & Compatibility

Vetmedin (Pimobendan) Chewable Tablets for Dogs

Vetmedin Chewable Tablets are a specialized veterinary inodilator medication formulated for oral administration in dogs to manage the clinical signs of congestive heart failure (CHF) originating from myxomatous mitral valve disease (MMVD) or dilated cardiomyopathy (DCM). Containing the active inotropic and vasodilating compound pimobendan, this professional-grade therapeutic preparation increases myocardial contractility while dilating both blood vessels to reduce the workload on the failing heart. Because advanced cardiovascular management requires accurate weight-based dosing and ongoing veterinary monitoring, administration must be guided by clinical supervision.

What Is Vetmedin?

Vetmedin is a specialized veterinary inodilator compound formulated for oral delivery under professional veterinary supervision.

Active Ingredients and Formulation

  • Active Component: Pimobendan at distinct milligram strengths per chewable tablet (1.25 mg, 2.5 mg, 5 mg, or 10 mg). It acts as a dual-action agent by exerting a positive inotropic effect through phosphodiesterase III (PDE III) inhibition and calcium sensitization, alongside a vasodilating effect via PDE III inhibition.

  • Vehicle and Presentation: Supplied as scored, flavored chewable tablets packaged in bottles or blister packs designed for precise, customizable dosing across canine patients of varying sizes.

What Is It Used For?

Primary Veterinary Indications

  • Management of Congestive Heart Failure: Routinely prescribed by veterinarians to manage clinical signs of congestive heart failure in dogs, addressing conditions such as mitral valve insufficiency and dilated cardiomyopathy.

  • Cardioprotective Support: Helps improve cardiac output, decrease heart size, alleviate pulmonary congestion, and enhance overall quality of life and exercise tolerance in cardiac patients.

Administration and Dosage Considerations

Route and Dosing

  • Route of Administration: Administered orally approximately one hour before feeding, as food significantly reduces the bioavailability of pimobendan.

  • Standard Canine Dosage Reference:

    • Total daily target dose is approximately 0.23 mg to 0.46 mg per pound (0.5 mg to 1.0 mg per kg) of body weight.

    • The total daily dose is divided into two equal portions, administered approximately 12 hours apart (e.g., morning and evening).

  • Veterinary Supervision: Comprehensive cardiac evaluations, echocardiograms, and precise body weight measurements must be performed by a licensed veterinarian before initiating and maintaining pimobendan therapy.

Important Safety Information

  • Contraindications: Do not administer in cases of hypertrophic cardiomyopathy, aortic stenosis, or other conditions where cardiac output cannot be functionally increased for anatomical reasons. Do not use in dogs with known hypersensitivity to pimobendan.

  • Side Effects and Precautions: Generally well tolerated. Potential adverse reactions may include decreased appetite, lethargy, diarrhea, dyspnea, azotemia, or mild increases in heart rate. Use with caution in breeding, pregnant, or lactating dogs.

  • Professional Guidance: Administer tablets strictly on an empty stomach about one hour before meals to maximize systemic absorption and therapeutic efficacy.

Storage and Handling

  • Store at controlled room temperature between 15°C and 30°C (59°F to 86°F). Keep the bottle tightly closed or blister packs securely sealed.

  • Keep individual chewables stored securely in their protective packaging until ready for immediate administration.

  • Keep securely out of reach of children, unauthorized individuals, and pets at all times.

Frequently Asked Questions

What is Vetmedin used for?

It is a prescription inodilator chewable tablet utilized to manage clinical signs of congestive heart failure caused by mitral valve disease or dilated cardiomyopathy in dogs.

What is the active ingredient?

Each tablet contains pimobendan, a dual-action drug that strengthens heart muscle contractions and dilates blood vessels to ease cardiac workload.

How is Vetmedin administered?

It is given orally twice daily, ideally about one hour before meals, with dosages calculated precisely based on your dog’s exact body weight.

Order Vetmedin Chews Online

Rx Vetmedin Chewable Tablets for Dogs are available for order through our platform subject to veterinary prescription verification and regulatory compliance. For assistance regarding prescription submission, dosing calculations, or secure shipping protocols, please contact our customer support team.

Additional information

Size

1.25 mg, 2.5 mg, 5 mg, 10 mg

Count

50 Tablets

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