Apoquel (Oclacitinib) Tablets for Dogs by Zoetis, 3.6 mg, 5.4 mg, or 16 mg

Apoquel Tablets are a specialized veterinary Janus kinase (JAK) inhibitor formulated for oral administration in dogs to control pruritus associated with allergic dermatitis and to control atopic dermatitis. Containing the active targeted immunomodulating compound oclacitinib maleate, this professional-grade therapeutic preparation rapidly blocks specific pro-inflammatory and pruritogenic cytokine pathways in the immune system to provide fast relief from severe itching and skin irritation. Because targeted immunomodulation requires accurate diagnosis and ongoing health evaluations, administration must be guided by veterinary clinical supervision.

What Is Apoquel?

Apoquel is a specialized veterinary targeted JAK inhibitor compound formulated for oral delivery under professional veterinary supervision.

Active Ingredients and Formulation

• Active Component: Oclacitinib (as oclacitinib maleate) at concentrations of 3.6 mg, 5.4 mg, or 16 mg per scored tablet. It acts as a selective inhibitor of Janus kinase enzymes (primarily JAK1), blocking the signaling pathways of key cytokines responsible for allergic inflammation and pruritus.

• Vehicle and Presentation: Supplied as scored oral tablets packaged in bottles of 100 counts designed for precise, customizable dosing across small and large canine patients 12 months of age and older.

What Is It Used For?

Primary Veterinary Indications

• Allergic Dermatitis Control: Routinely prescribed by veterinarians for the rapid control of pruritus (itching) associated with allergic dermatitis in dogs.

• Atopic Dermatitis Management: Indicated for the long-term control of atopic dermatitis and chronic skin allergies, helping eliminate self-inflicted trauma, redness, and secondary skin lesions.

Administration and Dosage Considerations

Route and Dosing

• Route of Administration: Administered orally, with or without food. The scored tablets can be easily split to ensure accurate weight-based dosing.

• Standard Canine Dosage Reference:

  • Initial Induction Phase: Administered at 0.18 mg to 0.27 mg per lb (0.4 mg to 0.6 mg per kg) of body weight twice daily (every 12 hours) for up to 14 days.

  • Maintenance Phase: Following the initial 14-day induction, the same dose is reduced to once daily (every 24 hours) for long-term maintenance therapy using the lowest effective level.

• Veterinary Supervision: Dosage adjustments, transition schedules, and ongoing dermatological evaluations must be managed exclusively by a licensed veterinarian.

Important Safety Information

• Contraindications: Do not administer to dogs with known hypersensitivity to oclacitinib. Do not use in dogs under 12 months of age or in dogs with serious active infections. Do not use in breeding, pregnant, or lactating bitches.

• Side Effects and Precautions: Generally exceptionally well tolerated. Occasional side effects may include mild vomiting, diarrhea, anorexia, lethargy, or increased blood cholesterol and lowered leukocyte counts. Because it modulates immune function, it may increase susceptibility to infections or exacerbate pre-existing neoplastic conditions.

• Professional Guidance: Regular veterinary check-ups and monitoring blood panels are recommended during long-term therapy to ensure patient safety and therapeutic efficacy.

Storage and Handling

• Store at controlled room temperature between 20°C and 25°C (68°F to 77°F), with excursions permitted between 15°C and 30°C (59°F to 86°F). Keep in the original container.

• Keep the bottle tightly sealed when not in use to protect from moisture.

• Keep securely out of reach of children, unauthorized individuals, and pets at all times.

Frequently Asked Questions

What is Apoquel used for?

It is a professional veterinary targeted tablet utilized to provide rapid relief from severe itching (pruritus) and inflammation associated with allergic and atopic dermatitis in dogs.

What is the active ingredient?

Each tablet contains oclacitinib maleate (3.6 mg, 5.4 mg, or 16 mg), a Janus kinase (JAK) inhibitor that interrupts itch and inflammation signals in the immune system.

How is Apoquel administered?

It is administered orally twice daily for the first 14 days, then tapered down to once daily for maintenance following precise weight-based guidelines under veterinary supervision.

Order Rx Apoquel Tablets Online

Rx Apoquel (Oclacitinib) Tablets for Dogs by Zoetis are available for order through our platform subject to veterinary prescription verification and regulatory compliance. For assistance regarding prescription submission, stock availability, or secure shipping protocols, please contact our customer support team.