PromAce (Acepromazine Maleate) Injection for Horses & Pets, 50 mL

PromAce Injection is a potent veterinary neuroleptic and tranquilizing agent formulated for administration in horses, dogs, and cats to calm excitable animals, facilitate handling, and serve as a pre-anesthetic sedative. Containing the active phenothiazine derivative acepromazine maleate, this professional-grade therapeutic preparation depresses the central nervous system by blocking postsynaptic dopamine receptors in the brain, rapidly producing relaxation and reducing motor activity. Because potent tranquilization and central nervous system depression require precise weight-based dosing and careful clinical evaluation, administration must be guided by strict veterinary supervision.

What Is PromAce Injection?

PromAce Injection is a specialized veterinary phenothiazine tranquilizing compound formulated for professional administration under direct veterinary supervision.

Active Ingredients and Formulation

• Active Component: Acepromazine maleate at a concentration of 10 mg/mL. It acts as a central nervous system depressant and dopamine antagonist, producing sedation, muscle relaxation, and a reduction in spontaneous activity without inducing true anesthesia.

• Vehicle and Presentation: Supplied as a sterile, clear aqueous solution in 50 mL multi-dose glass vials formulated for intravenous, intramuscular, or subcutaneous injection across equine and small animal patients.

What Is It Used For?

Primary Veterinary Indications

• Equine Handling and Sedation: Routinely prescribed by veterinarians to calm horses during clipping, shoeing, dental procedures, transport, and minor clinical examinations.

• Pre-Anesthetic Sedation: Utilized as a pre-anesthetic agent in dogs, cats, and horses to reduce the amount of general anesthetic required and to ensure smooth induction and recovery.

• Control of Apprehension: Manages nervousness, excitement, or acute fright in animals undergoing stressful environments or medical treatments.

Administration and Dosage Considerations

Route and Dosing

• Route of Administration: Administered via intravenous (IV), intramuscular (IM), or subcutaneous (SC) injection, using strict aseptic technique. Intravenous administration in horses must be performed slowly to prevent acute hypotensive collapse.

• Standard Dosage Reference:

  • Horses: Typically administered at 2 mg to 4 mg per 100 lbs of body weight intravenously, or 4 mg to 8 mg per 100 lbs intramuscularly.

  • Dogs and Cats: Typically administered at 0.25 mg to 0.5 mg per pound of body weight, adjusted according to the desired depth of sedation.

• Veterinary Supervision: Dosage must be adjusted carefully based on the age, breed, temperament, and physical condition of the animal. Use with extreme caution in debilitated animals or giant/toy breeds.

Important Safety Information

• Contraindications: Do not administer to animals undergoing surgeries or procedures involving organic phosphate insecticides, as acepromazine potentiates their toxicity. Do not use in animals with a history of epilepsy, severe trauma, shock, or known hypersensitivity to phenothiazines.

• Side Effects and Precautions: May cause profound hypotension, bradycardia, hypothermia, and prolapse of the nictitating membrane (third eyelid). Stallions may experience permanent penile prolapse due to retractor penis muscle relaxation.

• Professional Guidance: Animals recovering from acepromazine sedation should be kept in a quiet, temperature-controlled environment away from bright lights and loud noises until full alertness returns.

Storage and Handling

• Store at controlled room temperature between 15°C and 30°C (59°F to 86°F). Protect product from direct exposure to intense light to prevent degradation.

• Once punctured, multi-dose vials should be utilized under strict aseptic technique; discard any remaining solution if cloudiness or discoloration develops.

• Keep securely out of reach of children, unauthorized individuals, and pets at all times.

Frequently Asked Questions

What is PromAce Injection used for?

It is a prescription veterinary tranquilizer and pre-anesthetic sedative used to calm horses and small pets, ease handling, and reduce anesthetic requirements.

What is the active ingredient?

Each milliliter contains 10 mg of acepromazine maleate, a phenothiazine derivative that blocks dopamine receptors in the central nervous system.

How is PromAce administered?

It is given via intravenous, intramuscular, or subcutaneous injection, with exact dosing calculated strictly according to body weight and species requirements.

Order PromAce Injection Online

Rx PromAce (Acepromazine Maleate) Injection 10 mg/mL 50 mL Vials are available for order through our platform subject to veterinary prescription verification and regulatory compliance. For assistance regarding prescription submission, species-specific dosing guidelines, or secure shipping protocols, please contact our customer support team.