Dexium SP (Dexamethasone Sodium Phosphate) Injection for Horses, 100 mL

Dexium SP Injection is a high-potency veterinary corticosteroid formulation engineered to provide rapid, potent anti-inflammatory, immunosuppressive, and anti-allergic therapy for horses. Containing the water-soluble ester dexamethasone sodium phosphate, this professional-grade therapeutic preparation delivers immediate systemic availability following parenteral administration, making it highly effective for managing acute inflammatory crises, severe allergic reactions, and musculoskeletal flare-ups. Because of its profound systemic impact on endocrine, metabolic, and immune functions, the administration of Dexium SP requires precise veterinary diagnosis, individualized dosing, and strict adherence to clinical safety guidelines.

What Is Dexium SP Injection?

Dexium SP is a specialized veterinary corticosteroid compound formulated for parenteral administration under professional clinical supervision.

Active Ingredients and Formulation

• Active Component: Dexamethasone sodium phosphate equivalent to 2 mg of dexamethasone base per mL (totaling 200 mg per 100 mL multi-dose vial). It acts as a highly potent synthetic glucocorticoid with minimal mineralocorticoid activity, providing robust anti-inflammatory action roughly 25 to 30 times more potent than hydrocortisone.

• Vehicle and Presentation: Supplied as a sterile, clear aqueous injectable solution in a multi-dose 100 mL glass or polymer vial designed for intravenous, intramuscular, or intra-articular administration.

What Is It Used For?

Primary Veterinary Indications

• Acute Musculoskeletal Inflammation: Routinely utilized by equine veterinarians to manage severe inflammation associated with acute arthritis, bursitis, tendinitis, and founder (laminitis).

• Allergic and Anaphylactic Crises: Administered for rapid emergency intervention during severe allergic reactions, insect bites, hives (urticaria), and acute respiratory distress associated with heaves (recurrent airway obstruction / asthma).

• Endotoxemia and Shock Support: Used as an adjunctive therapeutic agent in the stabilization of horses experiencing acute systemic shock or endotoxemia.

Administration and Dosage Considerations

Route and Dosing

• Route of Administration: Administered via intravenous (I.V.) or intramuscular (I.M.) injection. Can also be administered intra-articularly for localized joint inflammation under strict veterinary aseptic technique.

• Standard Equine Dosage Reference: Typically administered at 2.5 mg to 5 mg per 100 lb (1 mg to 2.5 mg per 50 lb) of body weight (approximately 1.25 mL to 2.5 mL per 100 lb), adjusted according to the severity of the condition and clinical response.

• Veterinary Supervision: Dosage and duration of treatment must be strictly managed and tapered by a licensed veterinarian to avoid abrupt withdrawal or prolonged hypothalamic-pituitary-adrenal (HPA) axis suppression.

Important Safety Information

• Contraindications: Do not administer to horses with active viral or fungal infections, chronic nephritis, active gastrointestinal ulceration, or those exhibiting Cushing’s disease (PPID) unless specifically directed. Strictly contraindicated in pregnant mares during the last trimester, as systemic corticosteroids can induce premature parturition or abortion.

• Side Effects and Precautions: Long-term or high-dose usage can lead to immunosuppression, laminitis (especially in susceptible equines), delayed wound healing, muscle wasting, and suppression of endogenous cortisol production.

• Withdrawal Periods: Mandatory meat and milk withdrawal intervals established by local regulatory authorities must be strictly observed prior to marketing animal products from treated food-producing equines for human consumption.

• Professional Guidance: Due to its potent systemic impact, use must be managed under direct veterinary clinical oversight.

Storage and Handling

• Store at controlled room temperature between 15°C and 30°C (59°F to 86°F), protected from direct sunlight and freezing temperatures.

• Maintain strict aseptic technique when puncturing the 100 mL multi-dose vial to prevent microbial contamination during repeated use.

• Keep securely out of reach of children, unauthorized individuals, and animals at all times.

Frequently Asked Questions

What is Dexium SP Injection used for?

It is a professional equine corticosteroid injection utilized to provide rapid relief from severe inflammation, acute allergic reactions, anaphylaxis, and musculoskeletal crises.

What is the active ingredient?

It contains dexamethasone sodium phosphate at 2 mg/mL, a potent synthetic glucocorticoid that inhibits inflammatory pathways and immune responses.

How is Dexium SP administered?

It is administered via intravenous or intramuscular injection (or intra-articularly) following precise weight-based dosing guidelines under veterinary supervision.

Order Rx Dexium SP Injection Online

Rx Dexium SP Injection (Dexamethasone Sodium Phosphate, 100 mL) is available for order through our platform subject to veterinary prescription verification and regulatory compliance. For assistance regarding prescription submission, stock availability, or secure shipping protocols, please contact our customer support team.