Legend (Hyaluronate Sodium) Injectable Solution for Horses, 10 mg/mL, 2 mL or 4 mL Vial

Legend Injectable Solution is a specialized veterinary glycosaminoglycan formulated for intravenous or intra-articular administration in horses to treat joint dysfunction, pain, and lameness associated with non-infectious osteoarthritis of the carpal and hock joints. Containing the active high-molecular-weight sodium hyaluronate, this professional-grade therapeutic preparation restores the normal viscoelastic properties of synovial fluid, coats articular cartilage, and reduces intra-articular inflammation. Because optimal joint management requires precise clinical diagnosis and aseptic technique, administration must be guided by a licensed veterinarian.

What Is Legend Injectable Solution?

Legend is a specialized veterinary chondroprotective and anti-inflammatory compound formulated for parenteral delivery under professional clinical supervision.

Active Ingredients and Formulation

• Active Component: Hyaluronate sodium at a concentration of 10 mg per mL (supplied in 2 mL intravenous vials containing 20 mg total, or 4 mL intra-articular vials containing 40 mg total). It acts as a primary structural component of synovial fluid and cartilage matrix, lubricating joint structures and suppressing inflammatory mediators.

• Vehicle and Presentation: Supplied as a sterile, clear, non-pyrogenic aqueous solution packaged in single-dose glass vials designed for professional veterinary administration.

What Is It Used For?

Primary Veterinary Indications

• Equine Osteoarthritis Management: Routinely prescribed by equine veterinarians to control joint pain, stiffness, and lameness associated with non-infectious degenerative joint disease in the carpus (knee) and hock joints.

• Synovial Fluid Restoration: Replenishes depleted hyaluronic acid in inflamed joints, improving lubrication, reducing friction, and protecting articular cartilage from excessive mechanical wear during athletic performance.

Administration and Dosage Considerations

Route and Dosing

• Route of Administration: Administered via intravenous (I.V.) injection or strict intra-articular (I.A.) injection (restricted to carpal and hock joints).

• Standard Equine Dosage Reference:

  • Intravenous Dosage: Typically 40 mg (4 mL of the 10 mg/mL solution) per adult horse, administered by slow intravenous injection. Treatment may be repeated at weekly intervals for up to 3 treatments as needed.

  • Intra-Articular Dosage: Typically 20 mg (2 mL of the 10 mg/mL solution) per affected joint, administered strictly aseptically by a veterinarian. May be repeated at weekly intervals for up to 2 treatments.

• Veterinary Supervision: Injection protocols, site selection, and retreatment intervals must be determined and monitored exclusively by a licensed veterinarian.

Important Safety Information

• Contraindications: Do not administer to horses with known hypersensitivity to hyaluronate sodium. Contraindicated in cases of known or suspected joint infections (septic arthritis).

• Side Effects and Precautions: Exceptionally well tolerated. When administered intra-articularly, transient exacerbation of joint swelling, heat, or pain can occasionally occur within 24 to 48 hours post-injection; if symptoms persist, evaluate for infection.

• Withdrawal Periods: Observe mandatory meat withdrawal intervals established by regulatory authorities if treating food-producing equines intended for human consumption (typically several days following the final injection, depending on regional regulations).

• Professional Guidance: Due to the technical requirements of joint injections and systemic administration, use must be managed under direct veterinary clinical oversight.

Features:

• FDA-approved injectable solution for joint dysfunction in horses
• Contains Hyaluronate Sodium, a key component of healthy joint fluid
• Helps reduce inflammation and improve lubrication within the joint capsule
• Indicated for use in the carpus or fetlock affected by equine osteoarthritis
• Supports comfort, flexibility, and overall joint performance

Directions:

Administer 4 mL by slow intravenous injection using aseptic technique. Treatment may be repeated weekly for up to three total treatments, as directed by a veterinarian. Horses should be rested after administration before resuming normal activity. Discard any unused portion of the vial after opening.

Ingredients:

Hyaluronate Sodium 10 mg/mL

Storage and Handling

• Store at controlled room temperature between 15°C and 30°C (59°F to 86°F). Avoid excessive heat and freezing.

• Maintain strict aseptic technique when puncturing the vial stopper. Discard any unused portion.

• Keep securely out of reach of children, unauthorized individuals, and animals at all times.

Frequently Asked Questions

What is Legend Injectable Solution used for?

It is a professional equine hyaluronic acid injection utilized to relieve joint pain, reduce inflammation, and restore synovial fluid viscosity in horses with osteoarthritis.

What is the active ingredient?

It contains hyaluronate sodium at 10 mg/mL, a natural lubricating molecule that protects cartilage and cushions joint structures.

How is Legend administered?

It is administered via slow intravenous injection or strict intra-articular joint injection following precise clinical guidelines under veterinary supervision.

Order Rx Legend Injectable Solution Online

Rx Legend (Hyaluronate Sodium) Injectable Solution for Horses is available for order through our platform subject to veterinary prescription verification and regulatory compliance. For assistance regarding prescription submission, stock availability, or secure shipping protocols, please contact our customer support team.