Regu-Mate (Altrenogest) Oral Solution for Horses, 0.22%, 1000 mL

Regu-Mate Oral Solution is a specialized veterinary progestin formulation designed for oral administration in mares to suppress estrus (heat), synchronize estrus cycles, and maintain equine pregnancy in specific clinical scenarios. Containing the active synthetic progestogen altrenogest, this professional-grade therapeutic preparation mimics the natural corpus luteum hormone progesterone to regulate the hypothalamic-pituitary-ovarian axis. Because altrenogest is a potent bioactive progestin that poses significant absorption risks to humans, administration requires strict safety protocols, precise weight-based dosing, and direct veterinary clinical oversight.

What Is Regu-Mate Oral Solution?

Regu-Mate is a specialized veterinary progestational compound formulated for oral delivery under professional veterinary supervision.

Active Ingredients and Formulation

• Active Component: Altrenogest at a concentration of 2.2 mg per mL (0.22% weight/volume). It acts as a potent oral progestin that suppresses follicular activity and prevents behavioral estrus in mares.

• Vehicle and Presentation: Supplied as a clear, oily solution packaged in a multi-dose 1000 mL bottle equipped with a calibrated dosing dispenser designed for daily oral administration.

What Is It Used For?

Primary Veterinary Indications

• Estrus Suppression and Behavioral Management: Routinely prescribed by equine veterinarians to suppress estrus in cycling mares to eliminate erratic behavior, training difficulties, and discomfort associated with the heat cycle.

• Estrus Synchronization: Utilized in breeding operations to synchronize estrus cycles across groups of mares to facilitate scheduled breeding management.

• Pregnancy Maintenance: Administered under strict veterinary protocols to maintain pregnancy in mares with a history of early embryonic loss due to inadequate endogenous progesterone production.

Administration and Dosage Considerations

Route and Dosing

• Route of Administration: Administered orally, typically by squirting the solution directly onto the mare’s daily feed ration using a calibrated dosing pump or syringe.

• Standard Equine Dosage Reference: The recommended dosage is 0.044 mg per kg (0.02 mg per lb) of body weight (equivalent to 1 mL of solution per 110 lb) once daily for 15 consecutive days, or as directed by a licensed reproductive veterinarian for specialized synchronization and pregnancy support protocols.

• Veterinary Supervision: Treatment duration and precise dosing schedules must be determined and monitored exclusively by a qualified veterinarian.

Important Safety Information

• Contraindications: Do not administer to mares with pre-existing uterine infections (endometritis) or known hypersensitivity to altrenogest. Do not use in male horses or horses intended for human consumption.

• Human Safety Warnings (Critical): Altrenogest is readily absorbed through human skin and can cause severe endocrine disruption. Pregnant women, women of childbearing age, and individuals with known or suspected progestin-sensitive tumors must avoid handling this product entirely. Caregivers must wear protective disposable gloves (nitrile or rubber) whenever handling the bottle, measuring device, or feeding treated rations.

• Side Effects and Precautions: Generally well tolerated. Prolonged or improper use can occasionally lead to extended inter-ovulatory intervals following cessation of therapy.

Storage and Handling

• Store at controlled room temperature between 15°C and 30°C (59°F to 86°F). Protect from excessive heat and direct sunlight.

• Keep the bottle tightly capped when not in use.

• Keep securely out of reach of children, unauthorized individuals, and animals at all times.

Frequently Asked Questions

What is Regu-Mate Oral Solution used for?

It is a professional equine progestin liquid utilized to suppress estrus behavior, synchronize breeding cycles, and support pregnancy maintenance in mares.

What is the active ingredient?

It contains altrenogest at 2.2 mg/mL (0.22%), a synthetic progestogen that mimics natural progesterone to regulate ovarian activity.

How is Regu-Mate administered?

It is administered orally once daily by dosing over the feed using calibrated equipment, observing strict glove-wearing safety protocols due to skin absorption risks.

Order Rx Regu-Mate Oral Solution Online

Rx Regu-Mate (Altrenogest) Oral Solution for Horses (1000 mL) is available for order through our platform subject to veterinary prescription verification and safety compliance. For assistance regarding prescription submission, stock availability, or secure shipping protocols, please contact our customer support team.