Rompun (Xylazine) Injection for Horses, 100 mg/mL, 50 mL

Rompun Injection is a specialized veterinary sedative, analgesic, and muscle relaxant formulated for intravenous or intramuscular administration in horses to facilitate minor surgical procedures, diagnostic examinations, and standing sedation. Containing the potent alpha-2 adrenergic receptor agonist xylazine hydrochloride, this professional-grade therapeutic preparation rapidly produces central nervous system depression and profound analgesia. Because of its potent cardiovascular, respiratory, and autonomic effects, the administration of Rompun requires precise veterinary evaluation, individualized weight-based dosing, and strict adherence to clinical safety guidelines.

What Is Rompun Injection?

Rompun is a specialized veterinary alpha-2 agonist compound formulated for parenteral administration under professional veterinary supervision.

Active Ingredients and Formulation

• Active Component: Xylazine hydrochloride equivalent to 100 mg of xylazine base per mL. It acts as a selective alpha-2 adrenergic agonist, reducing sympathetic outflow from the central nervous system and producing sedation, analgesia, and muscle relaxation.

• Vehicle and Presentation: Supplied as a sterile, clear aqueous injectable solution in a multi-dose 50 mL glass vial designed for veterinary aseptic dispensing.

What Is Rompun Used For?

Primary Veterinary Indications

• Standing Sedation and Analgesia: Routinely utilized by equine veterinarians to calm nervous or fractious horses, facilitating clipping, shoeing, dental procedures, and physical examinations.

• Minor Surgical Procedures: Used as a standalone sedative or as a pre-anesthetic adjunct prior to local anesthesia or general anesthesia induction for minor field surgeries (such as wound suturing or castrations).

• Colic Pain Management: Administered to provide short-term visceral analgesia and sedation during acute equine colic evaluations prior to definitive diagnosis or transport.

Administration and Dosage Considerations

Route and Dosing

• Route of Administration: Administered via intravenous (I.V.) injection (preferred for rapid, reliable onset) or intramuscular (I.M.) injection (where onset is slower and effect is approximately twice the I.V. dose).

• Standard Equine Dosage Reference:

  • Intravenous: Typically administered at 0.5 mg per lb (1.1 mg per kg) of body weight (equivalent to 0.5 mL per 100 lb).

  • Intramuscular: Typically administered at 1.0 mg per lb (2.2 mg per kg) of body weight (equivalent to 1.0 mL per 100 lb).

• Veterinary Supervision: Must be administered solely by or under the direct supervision of a licensed veterinarian who can monitor cardiovascular parameters and patient stability.

Important Safety Information

• Contraindications: Do not administer to horses with pre-existing cardiac arrhythmias, heart block, severe respiratory depression, shock, or known hypersensitivity to xylazine. Do not use in late-term pregnant mares (unless inducing parturition), as it can induce premature uterine contractions.

• Side Effects and Precautions: Transient side effects include profound bradycardia, second-degree heart block, reduced cardiac output, mild respiratory depression, profuse sweating, and temporary ataxia (loss of coordination). Horses will lower their heads significantly; keep them in a safe, quiet environment away from sharp objects.

• Withdrawal Periods: Observe mandatory meat and milk withdrawal intervals established by local regulatory authorities if treating food-producing equines intended for human consumption.

• Professional Guidance: Due to its potent systemic impact on cardiovascular and respiratory function, use must be managed under direct veterinary clinical oversight.

Storage and Handling

• Store at controlled room temperature between 15°C and 30°C (59°F to 86°F), protected from direct sunlight and freezing temperatures.

• Maintain strict aseptic technique when puncturing the 50 mL multi-dose vial to prevent microbial contamination during repeated use.

• Keep securely out of reach of children, unauthorized individuals, and animals at all times.

Frequently Asked Questions

What is Rompun Injection used for?

It is a professional equine sedative and analgesic injection utilized to calm horses, provide pain relief during colic, and facilitate minor surgical or diagnostic procedures.

What is the active ingredient?

It contains xylazine hydrochloride at 100 mg/mL, which acts as an alpha-2 adrenergic agonist to depress the central nervous system and relax muscles.

How is Rompun administered to horses?

It is administered via intravenous or intramuscular injection following precise weight-based dosing guidelines under veterinary supervision.

Order Rx Rompun Injection Online

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