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PromAce (acepromazine maleate) Tablets for Horses, Dogs, & Cats

Promace is a prescription medication for dogs, cats & horses who suffer from motion sickness, anxiety or need a sedative to aid in minor procedures, such as examinations, treatments, groomings, nail trims, x-rays and minor surgical procedures.

Price range: $65.00 through $105.00

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Features & Compatibility

PromAce (Acepromazine Maleate) Tablets for Dogs, Cats, & Horses, 10 mg or 25 mg

PromAce Tablets are a dependable, professional-grade veterinary tranquilizer formulated for oral administration to calm and sedate dogs, cats, and horses. Containing the active phenothiazine derivative acepromazine maleate, this therapeutic preparation suppresses the central nervous system by blocking dopamine receptors in the brain, effectively reducing anxiety, excitability, and motor activity without producing profound unconsciousness. Because phenothiazine tranquilizers induce peripheral vasodilation and significant systemic effects, administration requires precise species-specific diagnosis, accurate weight-based dosing, and strict adherence to clinical safety protocols.

What Is PromAce?

PromAce is a specialized veterinary neuroleptic compound formulated for oral delivery under professional veterinary supervision.

Active Ingredients and Formulation

  • Active Component: Acepromazine maleate at a concentration of 10 mg or 25 mg per tablet. It acts as a potent central nervous system depressant and alpha-adrenergic blocking agent that calms fearful, aggressive, or hyperactive animals.

  • Vehicle and Presentation: Supplied as scored oral tablets packaged in bottles designed for convenient splitting and accurate dosing across multiple companion and large animal species.

What Is It Used For?

Primary Veterinary Indications

  • Anxiety and Stress Management: Routinely prescribed by veterinarians to calm animals experiencing situational anxiety associated with thunderstorms, fireworks, travel, grooming, or veterinary examinations.

  • Pre-Anesthetic Sedation: Utilized as a pre-anesthetic agent to ease induction, reduce the required dosage of general anesthetics, and provide smoother recoveries from surgical or diagnostic procedures.

  • Handling and Transport Support: Helps manage fractious, excitable, or high-strung horses and companion animals during clipping, shoeing, loading, or transport.

Administration and Dosage Considerations

Route and Dosing

  • Route of Administration: Administered orally, either given directly or crushed and mixed into a small portion of palatable food to ensure complete ingestion.

  • Standard Dosage Reference:

    • Canine (Oral): Typically 0.25 mg to 1.0 mg per lb (0.5 mg to 2.2 mg per kg) of body weight, adjusted based on the desired depth of sedation.

    • Feline (Oral): Typically 0.5 mg to 1.0 mg per lb (1.0 mg to 2.2 mg per kg) of body weight.

    • Equine (Oral): Typically 0.1 mg to 0.25 mg per lb (0.2 mg to 0.5 mg per kg) of body weight.

  • Veterinary Supervision: Dosage titration and timing must be determined exclusively by a licensed veterinarian based on individual temperament and health status.

Important Safety Information

  • Contraindications: Do not administer to animals with a history of epilepsy or seizure disorders (as it may lower the seizure threshold), hypovolemic shock, severe trauma, or known hypersensitivity to phenothiazines. Use with extreme caution in giant dog breeds, sighthounds, and boxer dogs due to heightened sensitivity.

  • Side Effects and Precautions: Causes peripheral vasodilation, which can result in transient hypotension (low blood pressure), hypothermia, and weakness. In male horses, acepromazine can cause permanent penile prolapse (paraphimosis); use with caution in breeding stallions.

  • Withdrawal Periods: Observe mandatory meat and milk withdrawal intervals established by regulatory authorities if treating food-producing equines or livestock intended for human consumption.

  • Professional Guidance: Due to its active cardiovascular and neurological impact, use must be managed under direct veterinary clinical oversight.

Storage and Handling

  • Store at controlled room temperature between 15°C and 30°C (59°F to 86°F), protected from light, moisture, and excessive heat.

  • Keep the container tightly sealed when not in use.

  • Keep securely out of reach of children, unauthorized individuals, and animals at all times.

Frequently Asked Questions

What is PromAce used for?

It is a professional veterinary tranquilizer tablet utilized to calm anxiety, manage travel stress, provide pre-anesthetic sedation, and facilitate handling in dogs, cats, and horses.

What is the active ingredient?

Each tablet contains acepromazine maleate (10 mg or 25 mg), a phenothiazine derivative that blocks central dopamine receptors to induce calming.

How are PromAce tablets administered?

They are administered orally, either directly or mixed into food, following precise weight-based guidelines under veterinary supervision.

Order Rx PromAce Tablets Online

Rx PromAce (Acepromazine Maleate) Tablets for Dogs, Cats, & Horses are available for order through our platform subject to veterinary prescription verification and regulatory compliance. For assistance regarding prescription submission, stock availability, or secure shipping protocols, please contact our customer support team.

Additional information

Size

10 mg, 25 mg

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