Prascend (Pergolide Tablets) for Horses, 1 mg, 160 ct

Prascend Tablets are a specialized veterinary dopamine receptor agonist formulated for oral administration in horses to manage the clinical signs associated with Pituitary Pars Intermedia Dysfunction (PPID), commonly known as Equine Cushing’s Disease. Containing the active ergot derivative pergolide mesylate, this professional-grade therapeutic preparation stimulates dopamine receptors in the pituitary gland to suppress the excessive secretion of adrenocorticotropic hormone (ACTH) and other hormones. Because PPID is a complex, progressive endocrine disorder requiring lifelong management, administration must be guided by accurate veterinary diagnosis, precise weight-based dosing, and strict adherence to clinical safety protocols.

What Is Prascend?

Prascend is a specialized veterinary endocrine compound formulated for oral delivery under professional veterinary supervision.

Active Ingredients and Formulation

• Active Component: Pergolide mesylate at a concentration of 1 mg per tablet. It acts as a potent, long-acting dopamine receptor agonist that binds to dopamine D2 receptors, inhibiting the overactivity of the pars intermedia in the equine pituitary gland.

• Vehicle and Presentation: Supplied as small, scored tablets packaged in a blister pack containing 160 tablets designed for convenient daily dosing.

What Is It Used For?

Primary Veterinary Indications

• Equine Cushing’s Disease (PPID): Routinely prescribed by equine veterinarians as the standard medical treatment to control the clinical signs of Pituitary Pars Intermedia Dysfunction in older horses and ponies.

• Symptom Management: Alleviates hallmark signs of PPID, including abnormal hair coat shedding (hirsutism/hypertrichosis), lethargy, muscle wasting, abnormal sweating, and polydipsia/polyuria.

• Laminitis Risk Reduction: Helps lower circulating ACTH levels to significantly reduce the risk of debilitating secondary laminitis associated with uncontrolled equine Cushing’s disease.

Administration and Dosage Considerations

Route and Dosing

• Route of Administration: Administered orally once daily, either given directly into the mouth or crushed and mixed into a small portion of feed or a palatable treat to ensure complete consumption.

• Standard Equine Dosage Reference: Typically initiated at an initial starting dose of 0.002 mg per lb (0.005 mg per kg) of body weight once daily (e.g., 1 mg tablet total for a 1,000 lb horse), adjusted by your veterinarian based on clinical response and follow-up blood hormone levels (ACTH testing).

• Veterinary Supervision: Dosage titration and long-term monitoring must be managed exclusively by a licensed veterinarian.

Important Safety Information

• Contraindications: Do not administer to horses with known hypersensitivity to pergolide or other ergot derivatives. Not approved for use in horses intended for human consumption.

• Side Effects and Precautions: Generally well tolerated, but transient side effects during initial dose adjustment can include decreased appetite, mild lethargy, or behavioral changes. If severe inappetence occurs, temporarily suspend treatment and consult your veterinarian.

• Handler Precautions: Caregivers should avoid crushing tablets and wear disposable gloves when handling the medication to prevent direct skin contact or inhalation.

• Professional Guidance: Due to its active endocrine profile and lifelong requirement, use must be managed under direct veterinary clinical oversight.

Storage and Handling

• Store at controlled room temperature below 25°C (77°F), with excursions permitted up to 30°C (86°F). Protect from light and moisture.

• Keep the blister pack sealed until ready for use.

• Keep securely out of reach of children, unauthorized individuals, and animals at all times.

Frequently Asked Questions

What is Prascend used for?

It is a professional equine endocrine medication utilized to manage Pituitary Pars Intermedia Dysfunction (Equine Cushing’s Disease) and its associated clinical symptoms in horses.

What is the active ingredient?

Each tablet contains 1 mg of pergolide mesylate, a dopamine receptor agonist that suppresses excessive hormone production in the equine pituitary gland.

How is Prascend administered?

It is administered orally once daily, either given directly or mixed into a small amount of feed according to precise veterinary guidance and ACTH monitoring.

Order Rx Prascend Tablets Online

Rx Prascend (Pergolide Tablets) for Horses (1 mg, 160 ct) is available for order through our platform subject to veterinary prescription verification and regulatory compliance. For assistance regarding prescription submission, stock availability, or secure shipping protocols, please contact our customer support team.